Epigenetics

Prediction of transcription factors associated with DNA demethylation during human cellular development.

***Chromosome Res. 2022 (2022) PMID: 35142952***

家族性血小板異常症(FPD)のエピゲノム解析

全がん状態のFPDのDNAメチル化異常を解明し、MDS/AMLへの進展メカニズムを解明する

DNAメチル化制御転写因子の解析

遺伝子のスイッチDNAメチル化の制御機序を解明する

A screening system to identify transcription factors that induce binding site-directed DNA demethylation

***Epigenetics Chromatin 10, 60 (2017) PMID: 29221486***

RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells

***blood advances 1, 20 (2017) PMID: 29296817***