- Original paper
-
- Single-Cell RNA-Seq Reveals LRRC75A-Expressing Cell Population Involved
in VEGF Secretion of Multipotent Mesenchymal Stromal/Stem Cells Under Ischemia
Takumi Miura, Tsukasa Kouno, Megumi Takano, Takuya Kuroda, Yumiko Yamamoto,
Shinji Kusakawa, Masaki Suimye Morioka, Tohru Sugawara, Takamasa Hirai, Satoshi Yasuda, Rumi Sawada, Satoko Matsuyama, Hideya
Kawaji, Takeya Kasukawa, Masayoshi Itoh, Akifumi Matsuyama, Jay W Shin,
Akihiro Umezawa, Jun Kawai, Yoji Sato
Stem Cells Transl Med 12(6) 379-390 2023年６月
- A single allele of the hsa-miR-302/367 cluster maintains human pluripotent
stem cells
Tohru Sugawara, Yuki Kawamoto, Tomoyuki Kawasaki, Akihiro Umezawa, Hidenori Akutsu
Regenerative Therapy 21 37-45 2022年5月
Using piggyBac transposon gene expression vectors to transfect Zscan5b
gene into mouse pluripotent stem cells
Mitsutoshi Yamada, Tohru Sugawara, Shinju Usami, Rina Nakanishi, Hidenori Akustu
STAR Protocol 2(3) 100811 2021年9月
The hsa-miR-302 cluster controls ectodermal differentiation of human pluripotent
stem cell via repression of DAZAP2.
Tohru Sugawara, Takumi Miura, Tomoyuki Kawasaki, Akihiro Umezawa, Hidenori Akutsu
Regenerative Therapy 15 1-9 2020年12月
Identification and therapeutic rescue of autophagosome and glutamate receptor
defects in C9ORF72 and sporadic ALS neurons.
Shi Y, Hung ST, Rocha G, Lin S, Linares GR, Staats KA, Seah C, Wang Y,
Chickering M, Lai J, Sugawara T, Sagare AP, Zlokovic BV, Ichida JK
JCI Insight 5 2019年7月
Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal
Aberrations during Mitosis.
Ogawa S, Yamada M, Nakamura A, Sugawara T, Nakamura A, Miyajima S, Harada Y, Ooka R, Okawa R, Miyauchi J, Tsumura
H, Yoshimura Y, Miyado K, Akutsu H, Tanaka M, Umezawa A, Hamatani T
Stem Cell Reports 12(6) 1366-1379 2019年6月
Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai
virus or episomal vectors.
Koichiro Nishino, Yoshikazu Arai, Ken Takasawa, Masashi Toyoda, Mayu Yamazaki-Inoue,
Tohru Sugawara, Hidenori Akutsu, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Akihiro
Umezawa
Regenerative Therapy 9 71-78 2018年12月
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human
induced motor neurons.
Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares
GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg
J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee
SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang
A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti
D, Zlokovic BV, Ichida JK
Nature Medicine 24(3) 313-325 2018年3月
Generation of primitive neural stem cells from human fibroblasts using
a defined set of factors
Takumi Miura, Tohru Sugawara, Atsushi Fukuda, Ryo Tamoto, Tomoyuki Kawasaki, Akihiro Umezawa, Hidenori
Akutsu
BIOLOGY OPEN 4(11) 1595-1607 2015年11月
Central role for PICALM in amyloid-β blood-brain barrier transcytosis
and clearance.
Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan
A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA,
Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV
Nature Neuroscience 18(7) 978-987 2015年7月
Xenogeneic-free defined conditions for derivation and expansion of human
embryonic stem cells with mesenchymal stem cells
Hidenori Akutsu, Masakazu Machida, Seiichi Kanzaki, Tohru Sugawara, Takashi Ohkura, Naoko Nakamura, Mayu Yamazaki-Inoue, Takumi Miura, Mohan
C. Vemuri, Mahendra S. Rao, Kenji Miyado, Akihiro Umezawa
Regenerative Therapy 1 18-29 2015年6月1日
β-catenin functions pleiotropically in differentiation and tumorigenesis
in mouse embryo-derived stem cells.
Okumura N, Akutsu H, Sugawara T, Miura T, Takezawa Y, Hosoda A, Yoshida K, Ichida JK, Yamada M, Hamatani
T, Kuji N, Miyado K, Yoshimura Y, Umezawa A
PLoS One 8(5) e63265 2013年5月
Correlation between Nuptial Colors and Visual Sensitivities Tuned by Opsins
Leads to Species Richness in Sympatric Lake Victoria Cichlid Fishes
Ryutaro Miyagi, Yohey Terai, Mitsuto Aibara, Tohru Sugawara, Hiroo Imai, Hidenori Tachida, Semvua Isa Mzighani, Takashi Okitsu, Akimori
Wada, Norihiro Okada
Molecular Biology and Evolution 29(11) 3281-3296 2012年11月
Eco-Geographical Diversification of Bitter Taste Receptor Genes (TAS2Rs)
among Subspecies of Chimpanzees (Pan troglodytes)
Takashi Hayakawa, Tohru Sugawara, Yasuhiro Go, Toshifumi Udono, Hirohisa Hirai, Hiroo Imai
PLoS One 7(8) e43277 2012年8月
Reverse Evolution in RH1 for Adaptation of Cichlids to Water Depth in
Lake Tanganyika
Haruka Nagai, Yohey Terai, Tohru Sugawara, Hiroo Imai, Hidenori Nishihara, Michio Hori, Norihiro Okada
Molecular Biology and Evolution 28(6) 1769-1776 2011年6月
Diversification of Bitter Taste Receptor Gene Family in Western Chimpanzees
Tohru Sugawara, Yasuhiro Go, Toshifumi Udono, Naruki Morimura, Masaki Tomonaga, Hirohisa
Hirai, Hiroo Imai
Molecular Biology and Evolution 28(2) 921-931 2011年2月
Identification of non-taster Japanese macaques for a specific bitter taste
Nami Suzuki, Tohru Sugawara, Atsushi Matsui, Yasuhiro Go, Hirohisa Hirai, Hiroo Imai
PRIMATES 51(4) 285-289 2010年10月
Vertebrate Rhodopsin Adaptation to Dim Light via Rapid Meta-II Intermediate
Formation
Tohru Sugawara, Hiroo Imai, Masato Nikaido, Yasushi Imamoto, Norihiro Okada
Molecular Biology and Evolution 27(3) 506-519 2010年3月
Divergent selection on opsins drives incipient speciation in Lake Victoria
cichlids
Yohey Terai, Ole Seehausen, Takeshi Sasaki, Kazuhiko Takahashi, Shinji
Mizoiri, Tohru Sugawara, Tetsu Sato, Masakatsu Watanabe, Nellie Konijnendijk, Hillary D. J. Mrosso,
Hidenori Tachida, Hiroo Imai, Yoshinori Shichida, Norihiro Okada
PLoS Biology 4(12) 2244-2251 2006年12月
Parallelism of amino acid changes at the RH1 affecting spectral sensitivity
among deep-water cichlids from Lakes Tanganyika and Malawi
T Sugawara, Y Terai, H Imai, GF Turner, S Koblmuller, C Sturmbauer, Y Shichida, N
Okada
Proceedings of the National Academy of Sciences of the United States of
America 102(15) 5448-5453 2005年4月
Natural selection of the rhodopsin gene during the adaptive radiation
of East African Great Lakes Cichlid fishes
T Sugawara, Y Terai, N Okada
Molecular Biology and Evolution 19(10) 1807-1811 2002年10月
- Review
- Organoids recapitulate organs?
Tohru Sugawara, Kengo Sasaki, Hidenori Akutsu
Stem Cell Investigation 5 3-3 2018年
Investigating cellular identity and manipulating cell fate using induced
pluripotent stem cells
Tohru Sugawara, Koichiro Nishino, Akihiro Umezawa, Hidenori Akutsu
STEM CELL RESEARCH & THERAPY 3(2) 8 2012年3月
- Book
- Post genome biology of primates focusing on taste perception
Tohru Sugawara and Hiroo Imai
in Post-Genome Biology of Primates (Primatology Monographs) 2012