発表論文

1.The role of the distal histidine in myoglobin and haemoglobin.

Olson JS, Mathews AJ, Rohlfs RJ, Springer BA, Egeberg KD, Sligar SG, Tame J, Renaud JP, Nagai K.

Nature. 1988 Nov 17;336(6196):265-6.

2.Structural and functional consequences of amino acid substitutions in hemoglobin as manifested in natural and artificial mutants.

Imai K, Shih DT, Tame J, Nagai K, Miyazaki G.

Protein Seq Data Anal. 1989 Feb;2(2):81-6.

3.NMR study of human mutant hemoglobins synthesized in Escherichia coli. Consequences of tyrosine alpha 42 substitutions.

Ishimori K, Morishima I, Imai K, Fushitani K, Miyazaki G, Shih D, Tame J, Pegnier J, Nagai K.

J Biol Chem. 1989 Sep 5;264(25):14624-6.

4.The effects of E7 and E11 mutations on the kinetics of ligand binding to R state human hemoglobin.

Mathews AJ, Rohlfs RJ, Olson JS, Tame J, Renaud JP, Nagai K.

J Biol Chem. 1989 Oct 5;264(28):16573-83.

5.Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering.

Lin SH, Yu NT, Tame J, Shih D, Renaud JP, Pagnier J, Nagai K.

Biochemistry. 1990 Jun 12;29(23):5562-6.

6.Functional role of the distal valine (E11) residue of alpha subunits in human haemoglobin.

Tame J, Shih DT, Pagnier J, Fermi G, Nagai K.

J Mol Biol. 1991 Apr 20;218(4):761-7.

7.Site-directed mutagenesis in haemoglobin. Functional role of tyrosine-42(C7) alpha at the alpha 1-beta 2 interface.

Imai K, Fushitani K, Miyazaki G, Ishimori K, Kitagawa T, Wada Y, Morimoto H, Morishima I, Shih DT, Tame J.

J Mol Biol. 1991 Apr 20;218(4):769-78.

8.Was the loss of the D helix in alpha globin a functionally neutral mutation?

Komiyama NH, Shih DT, Looker D, Tame J, Nagai K.

Nature. 1991 Jul 25;352(6333):349-51.

9.Adaptation of bird hemoglobins to high altitudes: demonstration of molecular mechanism by protein engineering.

Jessen TH, Weber RE, Fermi G, Tame J, Braunitzer G.

Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6519-22.

10.The assignment of carbon monoxide association rate constants to the alpha and beta subunits in native and mutant human deoxyhemoglobin tetramers.

Mathews AJ, Olson JS, Renaud JP, Tame J, Nagai K.

J Biol Chem. 1991 Nov 15;266(32):21631-9.

11.Mutant hemoglobins (alpha 119-Ala and beta 55-Ser): functions related to high-altitude respiration in geese.

Weber RE, Jessen TH, Malte H, Tame J.

J Appl Physiol. 1993 Dec;75(6):2646-55.

12.Production of human hemoglobin in Escherichia coli using cleavable fusion protein expression vector.

Jessen TH, Komiyama NH, Tame J, Pagnier J, Shih D, Luisi B, Fermi G, Nagai K.

Methods Enzymol. 1994;231:347-64. No abstract available.

13.The structural basis of sequence-independent peptide binding by OppA protein.

Tame JR, Murshudov GN, Dodson EJ, Neil TK, Dodson GG, Higgins CF, Wilkinson AJ.

Science. 1994 Jun 10;264(5165):1578-81.

14.Structure determination of OppA at 2.3 A resolution using multiple-wavelength anomalous dispersion methods.

Glover ID, Denny RC, Nguti ND, McSweeney SM, Kinder SH, Thompson AW, Dodson EJ, Wilkinson AJ, Tame JR.

Acta Crystallogr D Biol Crystallogr. 1995 Jan 1;51(Pt 1):39-47.

15.Transplanting a unique allosteric effect from crocodile into human haemoglobin.

Komiyama NH, Miyazaki G, Tame J, Nagai K.

Nature. 1995 Jan 19;373(6511):244-6.

16.The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands.

Tame JR, Dodson EJ, Murshudov G, Higgins CF, Wilkinson AJ.

Structure. 1995 Dec 15;3(12):1395-406.

17.The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form).

Zhang J, Hua Z, Tame JR, Lu G, Zhang R, Gu X.

J Mol Biol. 1996 Jan 26;255(3):484-93.

18.Crystal structure of T state haemoglobin with oxygen bound at all four haems.

Paoli M, Liddington R, Tame J, Wilkinson A, Dodson G.

J Mol Biol. 1996 Mar 8;256(4):775-92.

19.The crystal structures of trout Hb I in the deoxy and carbonmonoxy forms.

Tame JR, Wilson JC, Weber RE.

J Mol Biol. 1996 Jun 21;259(4):749-60.

20.A hemoglobin-based blood substitute: transplanting a novel allosteric effect of crocodile Hb.

Komiyama N, Tame J, Nagai K.

Biol Chem. 1996 Sep;377(9):543-8. Review.

21.The role of water in sequence-independent ligand binding by an oligopeptide transporter protein.

Tame JR, Sleigh SH, Wilkinson AJ, Ladbury JE.

Nat Struct Biol. 1996 Dec;3(12):998-1001. No abstract available.

22.Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine.

Sleigh SH, Tame JR, Dodson EJ, Wilkinson AJ.

Biochemistry. 1997 Aug 12;36(32):9747-58.

23.Scoring functions: a view from the bench.

Tame JR.

J Comput Aided Mol Des. 1999 Mar;13(2):99-108.

24.Relating structure to thermodynamics: the crystal structures and binding affinity of eight OppA-peptide complexes.

Davies TG, Hubbard RE, Tame JR.

Protein Sci. 1999 Jul;8(7):1432-44.

25.Crystallographic and calorimetric analysis of peptide binding to OppA protein.

Sleigh SH, Seavers PR, Wilkinson AJ, Ladbury JE, Tame JR.

J Mol Biol. 1999 Aug 13;291(2):393-415.

26.What is the true structure of liganded haemoglobin?

Tame JR.

Trends Biochem Sci. 1999 Oct;24(10):372-7.

27.Specificity and interactions of the protein OppA: partitioning solvent binding effects using mass spectrometry.

Rostom AA, Tame JR, Ladbury JE, Robinson CV.

J Mol Biol. 2000 Feb 11;296(1):269-79.

28.The structures of deoxy human haemoglobin and the mutant Hb Tyralpha42His at 120 K.

Tame JR, Vallone B.

Acta Crystallogr D Biol Crystallogr. 2000 Jul;56(Pt 7):805-11.

29.Ab initio phasing of a 4189-atom protein structure at 1.2 A resolution.

Tame JR.

Acta Crystallogr D Biol Crystallogr. 2000 Dec;56(Pt 12):1554-9.

30.The functional similarity and structural diversity of human and cartilaginous fish hemoglobins.

Naoi Y, Chong KT, Yoshimatsu K, Miyazaki G, Tame JR, Park SY, Adachi S, Morimoto H.

J Mol Biol. 2001 Mar 16;307(1):259-70.

31.The dimerization interface of the metastasis-associated protein S100A4 (Mts1): in vivo and in vitro studies.

Tarabykina S, Scott DJ, Herzyk P, Hill TJ, Tame JR, Kriajevska M, Lafitte D, Derrick PJ, Dodson GG, Maitland NJ, Lukanidin EM, Bronstein IB.

J Biol Chem. 2001 Jun 29;276(26):24212-22. Epub 2001 Mar 16.

32.Proteolytic analysis of the FliH/FliI complex, the ATPase component of the type III flagellar export apparatus of Salmonella.

Minamino T, Tame JR, Namba K, Macnab RM.

J Mol Biol. 2001 Oct 5;312(5):1027-36.

33.Purification of the autotransporter protein Hbp of Escherichia coli.

van Dooren SJ, Tame JR, Luirink J, Oudega B, Otto BR.

FEMS Microbiol Lett. 2001 Nov 27;205(1):147-50.

34.Low resolution solution structure of the Apo form of Escherichia coli haemoglobin protease Hbp.

Scott DJ, Grossmann JG, Tame JR, Byron O, Wilson KS, Otto BR.

J Mol Biol. 2002 Feb 1;315(5):1179-87.

35.The crystal structure of HpcE, a bifunctional decarboxylase/isomerase with a multifunctional fold.

Tame JR, Namba K, Dodson EJ, Roper DI.

Biochemistry. 2002 Mar 5;41(9):2982-9.

36.Crystal structures of deoxy- and carbonmonoxyhemoglobin F1 from the hagfish Eptatretus burgeri.

Mito M, Chong KT, Miyazaki G, Adachi S, Park SY, Tame JR, Morimoto H.

J Biol Chem. 2002 Jun 14;277(24):21898-905. Epub 2002 Mar 28.

37.Characterization and crystallization of a novel haemoglobinase from pathogenic Escherichia coli.

Tame JR, van Dooren SJ, Oudega B, Otto BR.

Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):843-5. Epub 2002 Apr 26.

38.Crystal structure of horse carbonmonoxyhemoglobin-bezafibrate complex at 1.55-A resolution. A novel allosteric binding site in R-state hemoglobin.

Shibayama N, Miura S, Tame JR, Yonetani T, Park SY.

J Biol Chem. 2002 Oct 11;277(41):38791-6. Epub 2002 Jul 16.

39.Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.

Kishida H, Wada T, Unzai S, Kuzuyama T, Takagi M, Terada T, Shirouzu M, Yokoyama S, Tame JR, Park SY.

Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):23-31. Epub 2002 Dec 19.

40.Crystal structure of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.

Wada T, Kuzuyama T, Satoh S, Kuramitsu S, Yokoyama S, Unzai S, Tame JR, Park SY.

J Biol Chem. 2003 Aug 8;278(32):30022-7. Epub 2003 May 27.

41.Direct observation of photolysis-induced tertiary structural changes in hemoglobin.

Adachi S, Park SY, Tame JR, Shiro Y, Shibayama N.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7039-44. Epub 2003 May 28.

42.Structure of a conserved CoA-binding protein synthesized by a cell-free system.

Wada T, Shirouzu M, Terada T, Ishizuka Y, Matsuda T, Kigawa T, Kuramitsu S, Park SY, Tame JR, Yokoyama S.

Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1213-8. Epub 2003 Jun 27.

43.Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8.

Handa N, Terada T, Kamewari Y, Hamana H, Tame JR, Park SY, Kinoshita K, Ota M, Nakamura H, Kuramitsu S, Shirouzu M, Yokoyama S.

Protein Sci. 2003 Aug;12(8):1621-32.

44.Interactions of FliJ with the Salmonella type III flagellar export apparatus.

Fraser GM, Gonzalez-Pedrajo B, Tame JR, Macnab RM.

J Bacteriol. 2003 Sep;185(18):5546-54.

45.Crystal structures of the liganded and unliganded nickel-binding protein NikA from Escherichia coli.

Heddle J, Scott DJ, Unzai S, Park SY, Tame JR.

J Biol Chem. 2003 Dec 12;278(50):50322-9. Epub 2003 Sep 5.

46.Crystal structure of the GTP-binding protein Obg from Thermus thermophilus HB8.

Kukimoto-Niino M, Murayama K, Inoue M, Terada T, Tame JR, Kuramitsu S, Shirouzu M, Yokoyama S.

J Mol Biol. 2004 Mar 26;337(3):761-70.

47.Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli.

Mizutani K, Machida Y, Unzai S, Park SY, Tame JR.

Biochemistry. 2004 Apr 20;43(15):4454-63.

48.Crystal structure of the conserved hypothetical protein TT1380 from Thermus thermophilus HB8.

Wada T, Shirouzu M, Terada T, Kamewari Y, Park SY, Tame JR, Kuramitsu S, Yokoyama S.

Proteins. 2004 May 15;55(3):778-80. No abstract available.

49.Novel mechanisms of pH sensitivity in tuna hemoglobin: a structural explanation of the root effect.

Yokoyama T, Chong KT, Miyazaki G, Morimoto H, Shih DT, Unzai S, Tame JR, Park SY.

J Biol Chem. 2004 Jul 2;279(27):28632-40. Epub 2004 Apr 26.

50.Crystal structure of elongation factor P from Thermus thermophilus HB8.

Hanawa-Suetsugu K, Sekine S, Sakai H, Hori-Takemoto C, Terada T, Unzai S, Tame JR, Kuramitsu S, Shirouzu M, Yokoyama S.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9595-600. Epub 2004 Jun 21.

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91.Influence of structural symmetry on protein dynamics.

Matsunaga Y, Koike R, Ota M, Tame JR, Kidera A.

PLoS One. 2012;7(11):e50011. doi: 10.1371/journal.pone.0050011. Epub 2012 Nov 26.

92.The structure of the deacetylase domain of Escherichia coli PgaB, an enzyme required for biofilm formation: a circularly permuted member of the carbohydrate esterase 4 family.

Nishiyama T, Noguchi H, Yoshida H, Park SY, Tame JR.

Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):44-51. doi: 10.1107/S0907444912042059. Epub 2012 Dec 20.

93.Capturing the hemoglobin allosteric transition in a single crystal form.

Shibayama N, Sugiyama K, Tame JR, Park SY.

J Am Chem Soc. 2014 Apr 2;136(13):5097-105. doi: 10.1021/ja500380e. Epub 2014 Mar 24.

94.The crystal structure of the active domain of Anopheles anti-platelet protein, a powerful anti-coagulant, in complex with an antibody.

Sugiyama K, Iyori M, Sawaguchi A, Akashi S, Tame JR, Park SY, Yoshida S.

J Biol Chem. 2014 Jun 6;289(23):16303-12. doi: 10.1074/jbc.M114.564526. Epub 2014 Apr 24.

95.Computational design of a self-assembling symmetrical β-propeller protein.

Voet AR, Noguchi H, Addy C, Simoncini D, Terada D, Unzai S, Park SY, Zhang KY, Tame JR.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15102-7. doi: 10.1073/pnas.1412768111. Epub 2014 Oct 6.

96.The structure and conformational switching of Rap1B.

Noguchi H, Ikegami T, Nagadoi A, Kamatari YO, Park SY, Tame JR, Unzai S.

Biochem Biophys Res Commun. 2015 Jun 19;462(1):46-51. doi: 10.1016/j.bbrc.2015.04.103. Epub 2015 Apr 29.

97.Biomineralization of a Cadmium Chloride Nanocrystal by a Designed Symmetrical Protein.

Voet AR, Noguchi H, Addy C, Zhang KY, Tame JR.

Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9857-60. doi: 10.1002/anie.201503575. Epub 2015 Jul 1.

98.The crystal and solution structure of YdiE from Escherichia coli.

Nishimura K, Addy C, Shrestha R, Voet AR, Zhang KY, Ito Y, Tame JR.

Acta Crystallogr F Struct Biol Commun. 2015 Jul;71(Pt 7):919-24. doi: 10.1107/S2053230X15009140. Epub 2015 Jun 27.

99.Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium.

Ohki M, Sugiyama K, Kawai F, Tanaka H, Nihei Y, Unzai S, Takebe M, Matsunaga S, Adachi S, Shibayama N, Zhou Z, Koyama R, Ikegaya Y, Takahashi T, Tame JR, Iseki M, Park SY.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6659-64. doi: 10.1073/pnas.1517520113. Epub 2016 May 31.

100.Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types.

Terada D, Kawai F, Noguchi H, Unzai S, Hasan I, Fujii Y, Park SY, Ozeki Y, Tame JR.

Sci Rep. 2016 Jun 20;6:28344. doi: 10.1038/srep28344.

101.Evolution-Inspired Computational Design of Symmetric Proteins.

Voet AR, Simoncini D, Tame JR, Zhang KY.

Methods Mol Biol. 2017;1529:309-322.

102.Protein-templated synthesis of metal-based nanomaterials.

Voet AR, Tame JR.

Curr Opin Biotechnol. 2017 Jan 11;46:14-19. doi: 10.1016/j.copbio.2016.10.015. [Epub ahead of print] Review.